AMH test – ovarian reserve
AMH testing is an effective way to determine a woman's fertility. AMH levels can help to diagnose premature ovarian failure as well as polycystic ovary syndrome. This is one of the first laboratory tests a woman should perform with the view to infertility treatment.
Anti-Müllerian Hormone (AMH)
AMH (Anti-Müllerian Hormone) is produced both by men and by women. In women, it has a very important function. It is secreted by the granular cells of preantral and antral follicles. Its task, together with the follicle stimulating hormone (FSH), is to regulate the maturing of the follicles in which the egg cell develops.
The level of AMH, which is closely related to a woman's fertility, allows not only to assess her chance of conceiving a child in a natural way, but also to select an appropriate hormone stimulation protocol for patients using the assisted reproduction method, such as an in vitro procedure.
The result of the AMH test allows to assess the possibility of Ovarian Hyperstimulation Syndrome (OHSS). A high level of AMH significantly increases the birth rate and also allows to determine the number of oocytes that can be obtained during an ovarian puncture.
Interpretation of the results
The AMH limit of normal is an indicative value, also dependent on age. For the sake of simplicity, values between 1 ng/mL and 3.0 ng/mL are assumed to be reference values for women at reproductive age. The AMH result should be consulted with a specialist who can refer a patient to further tests needed at a later stage of treatment.
The AMH levels should be consulted with a specialist who may order further tests needed later.
A low AMH level indicates a reduced ovarian reserve, i.e. a small number of ovarian follicles containing an egg cell. An AMH value below 1.0 ng/mL is an indication for consultation in a clinic specializing in the treatment of infertility for the diagnosis of premature ovarian failure.
Too high AMH
High levels of anti-Müllerian hormone (above 6 ng/mL) may indicate the so-called Polycystic Ovary Syndrome, or PCOS, which is manifested by the production of too many immature Graafian follicles, which has an endocrine disrupting impact on the female body. The cause of PCOS is seen in insulin resistance as well as excessive excretion of luteinizing (LH) and follicle stimulating (FSH) hormone by the pituitary gland. Persons suffering from polycystic ovary syndrome usually also suffer from hirsutism (excessive hair growth) and obesity
When to perform the test?
The determination of AMH levels in blood is the first step that should be taken by a woman who is unsuccessfully trying to conceive. The AMH test is also needed in order to join the municipal programmes subsidising in vitro infertility treatment at InviMed clinics in Warsaw, Gdynia, Poznań, Częstochowa and Sosnowiec. The minimum level of AMH to be eligible for a subsidy for the in vitro procedure is 0.7 ng/mL.
How to prepare for AMH test?
AMH level is measured on the basis of blood sample examination. AMH levels in the blood remain constant and are independent of the day of the cycle, regardless of taking contraception or hormone therapy. The AMH test does not require any special preparation by the patient. It is a painless test and can be performed at any time of the day, also regardless of the time that has passed since the last meal.
Where to perform the test?
The AMH level can be determined in any of our clinics. You can check the working hours of a collection point on our website in the contact tab. The AMH result can be collected after 4 working days.